MEKK1 is a JNK activating kinase known to be implicated in proinflammatory responses and cell motility. Using mice deficient for MEKK1 kinase activity
نویسندگان
چکیده
This work was supported in part by: The Danish Medical Research Councils (SSVF) The Alfred Benzon Foundation, The Johann Weiman f. Seedorff and wife Foundation (Købmand i Odense Johann og Hanne Weimann f. Seedorff’s Legat), The Leo Foundation, The Willumsen Foundation (Fabrikant Einar Willumsens Mindelegat), The Danielsen foundation (Aase og Ejnar Danielsens Fond), The Magnus Bergvall Foundation (Magnus Bergvalls Stiftelse), Else and Mogens Wedell-Wedellborgs Foundation, The Fraenkel Foundation (Eva og Henry Fraenkels Mindefond). University of Copenhagen. Blood First Edition Paper, prepublished online August 4, 2005; DOI 10.1182/blood-2005-04-1739
منابع مشابه
MEK kinase 1 activity is required for definitive erythropoiesis in the mouse fetal liver.
Mitogen-activated protein kinase/extracellular signal to regulated kinase (MEK) kinase 1 (MEKK1) is a c-Jun N-terminal kinase (JNK) activating kinase known to be implicated in proinflammatory responses and cell motility. Using mice deficient for MEKK1 kinase activity (Mekk1(DeltaKD)) we show a role for MEKK1 in definitive mouse erythropoiesis. Although Mekk1(DeltaKD) mice are alive and fertile ...
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